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Glycerol kinase Antibody (PA5-120997) in IHC (P)
Immunohistochemistry analysis of Glycerol kinase in paraffin-embedded human esophageal cancer. Samples were incubated with Glycerol kinase Polyclonal antibody (Product # PA5-120997) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-120997
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 422-559 of Glycerol kinase (GK) (NP_001191948.1).
偶联物
形式
Liquid
浓度
1.04 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914569
产品详细信息
Positive test controls include: DU145, U-87MG. The target is usually found in the following locations: Cytoplasm, Cytoplasmic side, Mitochondrion outer membrane, Peripheral membrane protein.
Immunogen sequence: GIPLSHLQVD GGMTSNKILM QLQADILYIP VVKPSMPETT ALGAAMAAGA AEGVGVWSLE PEDLSAVTME RFEPQINAEE SEIRYSTWKK AVMKSMGWVT TQSPESGDPS IFCSLPLGFF IVSSMVMLIG ARYISGIP
靶标信息
The product of this gene belongs to the FGGY kinase family of proteins and encodes glycerol kinase. Glycerol kinase is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Defects in this gene are the cause of glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASTP; ATP-stimulated glucocorticoid-receptor translocation promoter; ATP-stimulated glucocorticoid-receptor translocaton promoter; ATP:glycerol 3-phosphotransferase; EC 2.7.1.30; GK 3; GK3P; GKl; GKP3; GKTB; Glycerokinase; Glycerokinase 3; Glycerol kinase; Glycerolkinase
基因别名: ASTP; D930012N15Rik; GK; GK1; GKD; Gyk
UniProt ID: (Human) P32189, (Rat) Q63060, (Mouse) Q64516
Entrez Gene ID: (Human) 2710, (Rat) 79223, (Mouse) 14933
glycerol metabolic process
triglyceride metabolic process
response to cold
phosphorylation
regulation of fatty acid metabolic process
triglyceride biosynthetic process
glycerol catabolic process
response to drug
glucose homeostasis
response to ethanol
glycerol-3-phosphate biosynthetic process
glycerol-3-phosphate metabolic process
response to organic substance
carbohydrate metabolic process
