Product References
The Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and Function.
Molecular neurobiology
Pandolfi EC,Breuer JA,Nguyen Huu VA,Talluri T,Nguyen D,Lee JS,Hu R,Bharti K,Skowronska-Krawczyk D,Gorman MR,Mellon PL,Hoffmann HM
PA1-121 was used in Immunohistochemistry to identify VAX1, and confirm SIX6, as transcription factors required for suprachiasmatic nucleus (SCN) development and function.
Sat Feb 01 00:00:00 UTC 2020
Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems.
Scientific reports
Wang H,Parra M,Conboy JG,Hillyer CD,Mohandas N,An X
PA1-121 was used in Immunohistochemistry on paraffin embedded tissues to uncover a novel role for 4.1N in the axis of hypothalamus-pituitary gland-reproductive system.
Mon Oct 12 00:00:00 UTC 2020
Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems.
Scientific reports
Wang H,Parra M,Conboy JG,Hillyer CD,Mohandas N,An X
PA1-121 was used in Immunohistochemistry on paraffin embedded tissues to uncover a novel role for 4.1N in the axis of hypothalamus-pituitary gland-reproductive system.
Mon Oct 12 00:00:00 UTC 2020
Differential CRE Expression in Lhrh-cre and GnRH-cre Alleles and the Impact on Fertility in Otx2-Flox Mice.
Neuroendocrinology
Hoffmann HM,Larder R,Lee JS,Hu RJ,Trang C,Devries BM,Clark DD,Mellon PL
Published figure using GnRH1 polyclonal antibody (Product # PA1-121) in Immunohistochemistry
Thu Dec 26 00:00:00 UTC 2019
Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.
Frontiers in immunology
Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D
PA1-121 was used in Immunohistochemistry to study the neuro-immune mechanisms underlying sex-specific differences in obesity-induced impairment of the hypothalamic function with potential consequences for reproduction and fertility.
Wed Sep 25 00:00:00 UTC 2019
Sox21 deletion in mice causes postnatal growth deficiency without physiological disruption of hypothalamic-pituitary endocrine axes.
Molecular and cellular endocrinology
Cheung LYM,Okano H,Camper SA
PA1121 was used in immunohistochemistry to explore the role of Sox21 expression in hypothalamic-pituitary development
Thu Jan 05 00:00:00 UTC 2017
Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Hoffmann HM,Trang C,Gong P,Kimura I,Pandolfi EC,Mellon PL
PA1-121 was used in immunohistochemistry - paraffin section to study the abolishment of GnRH expression and leads to hypogonadism and infertility due to a deletion of Vax1 from gonadotropin-releasing hormone (GnRH) neurons
Wed Mar 23 00:00:00 UTC 2016
Distribution and regulation of gonadotropin-releasing hormone, kisspeptin, RF-amide related peptide-3, and dynorphin in the bovine hypothalamus.
PeerJ
Tanco VM,Whitlock BK,Jones MA,Wilborn RR,Brandebourg TD,Foradori CD
PA1-121 was used in immunohistochemistry - free floating to characterize bovine hypothalamus for distribution and regulation of gonadotropin-releasing hormone, RF-amide related peptide-3, kisspeptin, and dynorphin
Fri Mar 25 00:00:00 UTC 2016
In Utero Development of Kisspeptin/GnRH Neural Circuitry in Male Mice.
Endocrinology
Kumar D,Periasamy V,Freese M,Voigt A,Boehm U
PA1-121 was used in immunohistochemistry - frozen section to examine the role of kisspeptin/GPR54 in the developing brain
Tue Sep 01 00:00:00 UTC 2015
Olfactomedin 1 Deficiency Leads to Defective Olfaction and Impaired Female Fertility.
Endocrinology
Li R,Diao H,Zhao F,Xiao S,El Zowalaty AE,Dudley EA,Mattson MP,Ye X
PA1-121 was used in immunohistochemistry - frozen section to elucidate the mechanism by which olfactomedin 1 deficiency results in infertility
Tue Sep 01 00:00:00 UTC 2015
Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice.
Molecular and cellular endocrinology
Xie C,Jonak CR,Kauffman AS,Coss D
PA1-121 was used in immunohistochemistry to study reproductive function in cFOS-deficient mice
Sat Aug 15 00:00:00 UTC 2015
Chronic oestradiol reduces the dendritic spine density of KNDy (kisspeptin/neurokinin B/dynorphin) neurones in the arcuate nucleus of ovariectomised Tac2-enhanced green fluorescent protein transgenic mice.
Journal of neuroendocrinology
Cholanian M,Krajewski-Hall SJ,McMullen NT,Rance NE
PA1-121 was used in immunohistochemistry to assess the effect of oestrogens on the dendrites of neurons
Wed Apr 01 00:00:00 UTC 2015
Chronic oestradiol reduces the dendritic spine density of KNDy (kisspeptin/neurokinin B/dynorphin) neurones in the arcuate nucleus of ovariectomised Tac2-enhanced green fluorescent protein transgenic mice.
Journal of neuroendocrinology
Cholanian M,Krajewski-Hall SJ,McMullen NT,Rance NE
PA1-121 was used in immunohistochemistry to assess the effect of oestrogens on the dendrites of neurons
Wed Apr 01 00:00:00 UTC 2015
Murine arcuate nucleus kisspeptin neurons communicate with GnRH neurons in utero.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kumar D,Freese M,Drexler D,Hermans-Borgmeyer I,Marquardt A,Boehm U
PA1-121 was used in immunohistochemistry to study the in utero communication between gonadotropin-releasing hormone neurons and arcuate nucleus kisspeptin neurons
Wed Mar 05 00:00:00 UTC 2014
Murine arcuate nucleus kisspeptin neurons communicate with GnRH neurons in utero.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kumar D,Freese M,Drexler D,Hermans-Borgmeyer I,Marquardt A,Boehm U
PA1-121 was used in immunohistochemistry to study the in utero communication between gonadotropin-releasing hormone neurons and arcuate nucleus kisspeptin neurons
Wed Mar 05 00:00:00 UTC 2014
Conditional genetic transsynaptic tracing in the embryonic mouse brain.
Journal of visualized experiments : JoVE
Kumar D,Boehm U
PA1-121 was used in immunohistochemistry to describe a method for transsynaptic tracing in mouse embryos using the novel recombinant ROSA26 alleles
Mon Dec 22 00:00:00 UTC 2014
Developmental profile and sexually dimorphic expression of kiss1 and kiss1r in the fetal mouse brain.
Frontiers in endocrinology
Knoll JG,Clay CM,Bouma GJ,Henion TR,Schwarting GA,Millar RP,Tobet SA
PA1-121 was used in immunohistochemistry to study the developmental- and gender-dependent expression of kiss1 and kiss1r in fetal murine brain
Wed Oct 16 00:00:00 UTC 2013
Gene dosage of Otx2 is important for fertility in male mice.
Molecular and cellular endocrinology
Larder R,Kimura I,Meadows J,Clark DD,Mayo S,Mellon PL
PA1-121 was used in immunohistochemistry the study the effects of Otx2 gene dosage on the fertility of male mice
Thu Sep 05 00:00:00 UTC 2013
Lhx2-dependent specification of olfactory sensory neurons is required for successful integration of olfactory, vomeronasal, and GnRH neurons.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Berghard A,Hägglund AC,Bohm S,Carlsson L
PA1-121 was used in immunohistochemistry to study the role of Lhx2 in olfactory sensory neurons in olfactory, vomeronasal and GnRH neuron development
Wed Aug 01 00:00:00 UTC 2012
Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Larder R,Clark DD,Miller NL,Mellon PL
PA1-121 was used in immunohistochemistry to investigate the role of Six6 in the regulation of GnRH expression
Wed Jan 12 00:00:00 UTC 2011
Genetic identification of GnRH receptor neurons: a new model for studying neural circuits underlying reproductive physiology in the mouse brain.
Endocrinology
Wen S,Götze IN,Mai O,Schauer C,Leinders-Zufall T,Boehm U
PA1-121 was used in immunocytochemistry to evaluate a new mouse model to study the neuronal basis of reproductive physiology in the brain
Fri Apr 01 00:00:00 UTC 2011
Composition of the migratory mass during development of the olfactory nerve.
The Journal of comparative neurology
Miller AM,Treloar HB,Greer CA
PA1-121 was used in immunohistochemistry to investigate the neurnal migration during development of the olfactory nerve
Wed Dec 15 00:00:00 UTC 2010
Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development.
Human molecular genetics
Miller NL,Wevrick R,Mellon PL
PA1-121 was used in immunohistochemistry to study how necdin regulates gonadotropin-releasing hormone neurons during development
Thu Jan 15 00:00:00 UTC 2009
Loss of magel2, a candidate gene for features of Prader-Willi syndrome, impairs reproductive function in mice.
PloS one
Mercer RE,Wevrick R
PA1-121 was used in immunohistochemistry to study the role of Magel2 in reproductive function in mice
Fri May 01 00:00:00 UTC 2009
Heterogeneous expression of the potassium-chloride cotransporter KCC2 in gonadotropin-releasing hormone neurons of the adult mouse.
Endocrinology
Leupen SM,Tobet SA,Crowley WF,Kaila K
PA1-121 was used in immunohistochemistry to investigate the expression of the potassium-chloride cotransporter KCC2 in a subset of adult mouse neurons.
Tue Jul 01 00:00:00 UTC 2003
