Invitrogen

Golgi protein 58k Polyclonal Antibody

Golgi protein 58k Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Golgi protein 58k Antibody (PA5-22075) in IHC (P)

Immunohistochemistry (Paraffin) analysis of Golgi protein 58k was performed in paraffin-embedded human hepatocellular carcinoma tissue using Golgi protein 58k Polyclonal Antibody (Product # PA5-22075) at a dilution of 1:500.

Golgi protein 58k Antibody in Western Blot (WB)

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产品信息

PA5-22075

应用

建议稀释比

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免疫印迹 (WB)

1:500-1:3,000

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 1 and 251 of FTCD (Uniprot ID#O95954)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.98 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 10% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_11152309

产品详细信息

Recommended positive controls: HepG2, mouse liver, MDA-MB-231.

Predicted reactivity: Mouse (88%), Rat (89%), Pig (84%), Chicken (80%), Bovine (88%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Golgi Protein, 58K is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Formimidoyltransferase-cyclodeaminase; formiminotransferase cyclodeaminase; Formiminotransferase-cyclodeaminase; FTCD; glutamate formiminotransferase; LCHC1

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基因别名: FTCD; LCHC1

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UniProt ID: (Human) O95954, (Mouse) Q91XD4

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Entrez Gene ID: (Human) 10841, (Mouse) 14317

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功能

protein binding folic acid binding microtubule binding formimidoyltransferase activity glutamate formimidoyltransferase activity formimidoyltetrahydrofolate cyclodeaminase activity catalytic activity transferase activity lyase activity

参与通路

histidine metabolic process histidine catabolic process cytoskeleton organization metabolic process cellular metabolic process folic acid-containing compound metabolic process histidine catabolic process to glutamate and formamide histidine catabolic process to glutamate and formate tetrahydrofolate interconversion