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产品信息
PA5-57125
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2642201
产品详细信息
Immunogen sequence: ALNAWKENFM TVDQDGSGTV EHHELRQAIG LMGYRLSPQT LTTIVKRYSK NGRIFFDDY
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.
靶标信息
This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Grancalcin; grancalcin, EF-hand calcium binding protein; grancalcin, EF-hand calcium-binding protein; grancalcin, penta-EF-hand protein
基因别名: GCA; GCL
UniProt ID: (Human) P28676
Entrez Gene ID: (Human) 25801
