Invitrogen

H2A.Zac pan-acetyl (K4,K7,K11,K13) Polyclonal Antibody

H2A.Zac pan-acetyl (K4,K7,K11,K13) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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H2A.Zac pan-acetyl (K4,K7,K11,K13) Antibody (PA5-114690) in IHC (P)

Immunohistochemistry analysis of H2A.Zac pan-acetyl (K4,K7,K11, K13) in human gastric cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-114690) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.

H2A.Zac pan-acetyl (K4,K7,K11,K13) Antibody in Western Blot (WB)

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产品信息

PA5-114690

应用

建议稀释比

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免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human H2AFZ(Accession P0C0S5), corresponding to amino acid residues M1-S21.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2899326

产品详细信息

Antibody detects endogenous levels of Acetyl-H2A.Z only when acetylated at Lys4/7/11/13.

靶标信息

H2A.Zac pan-acetyl (K4,K7,K11,K13) is classified under histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

仅用于科研。不用于诊断过程。未经明确授权不得转售。