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Immunogen sequence: FVEVVIEGDA MSPDFIPSQP EGVYLYSKYR EPEKYIELDG DRLTTEDLVN LGKGRYKIKL TPTAEKRVQK SREVIDSIIK EKTVVYGITT GFGKFARTV
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.
HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.
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蛋白别名: Histidase; Histidine ammonia-lyase
基因别名: HAL; HIS; HSTD
UniProt ID: (Human) P42357
Entrez Gene ID: (Human) 3034