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Immunogen sequence: MPRYTVHVRG EWLAVPCQDA QLTVGWLGRE AVRRYIKNKP DNGGFTSVDD AHFLVRRCKG LGLLDNEDRL EVALENNEFV EVVIEGDAMS PDFIPSQPEG VYLYSKYREP EKYIELDGDR LTTEDLVNLG KGRYKIKLTP TAEKRVQKSR EVIDSIIKEK TVVYGITTGF GKFARTVIPI NKLQELQVNL VRSHSSGVGK; Positive Samples: Mouse liver, Rat liver
HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Histidase; Histidine ammonia-lyase; histidinemia
基因别名: HAL; HIS; histidase; Hsd; HSTD; Huth
UniProt ID: (Human) P42357, (Rat) P21213, (Mouse) P35492
Entrez Gene ID: (Human) 3034, (Rat) 29301, (Mouse) 15109