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Antibody detects endogenous levels of total HAMP.
HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Hepcidin; hepcidin antimicrobial peptide 1; LEAP-1; Liver-expressed antimicrobial peptide 1; PLTR; Putative liver tumor regressor
基因别名: HAMP; Hamp1; HEPC; Hepc1; HFE2B; LEAP1; PLTR; UNQ487/PRO1003
UniProt ID: (Human) P81172, (Mouse) Q9EQ21, (Rat) Q99MH3
Entrez Gene ID: (Human) 57817, (Mouse) 84506, (Rat) 84604