Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
HARS2 Antibody (PA5-96805) in WB
Western blot analysis of HARS2 in extracts of various cell lines. Samples were incubated with HARS2 Polyclonal antibody (Product # PA5-96805) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-96805
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 217-506 of human HARS2 (NP_0363401)
偶联物
形式
Liquid
浓度
9.51 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808607
产品详细信息
Immunogen sequence: IVDGMFAVCG VPESKFRAIC SSIDKLDKMA WKDVRHEMVV KKGLAPEVAD RIGDYVQCHG GVSLVEQMFQ DPRLSQNKQA LEGLGDLKLL FEYLTLFGIA DKISFDLSLA RGLDYYTGVI YEAVLLQTPT QAGEEPLNVG SVAAGGRYDG LVGMFDPKGH KVPCVGLSIG VERIFYIVEQ RMKTKGEKVR TTETQVFVAT PQKNFLQERL KLIAELWDSG IKAEMLYKNN PKLLTQLHYC ESTGIPLVVI IGEQELKEGV IKIRSVASRE EVAIKRENFV AEIQKRLSES; Positive Samples: U-251MG, Rat liver; Cellular Location: Mitochondrion matrix
靶标信息
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: EC 6.1.1.21; HARS-related; HisRS; histidine translase; histidine tRNA ligase 2, mitochondrial (putative); Histidine--tRNA ligase, mitochondrial; Histidine--tRNA ligase-like; histidine-tRNA ligase homolog; Histidyl-tRNA synthetase; histidyl-tRNA synthetase 2; histidyl-tRNA synthetase 2, mitochondrial (putative); probable histidine--tRNA ligase, mitochondrial; probable histidyl-tRNA synthetase, mitochondrial; zinc finger, matrin type 2
基因别名: 4631412B19Rik; HARS2; Hars2l; HARSL; HARSR; HO3; PRLTS2; RGD1308426; Zmat2
UniProt ID: (Human) P49590, (Mouse) Q99KK9
Entrez Gene ID: (Human) 23438, (Rat) 307491, (Mouse) 70791
