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HB9 Antibody (PA5-102932) in ICC/IF
Immunocytochemistry analysis of HB9 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with HB9 polyclonal antibody (Product # PA5-102932) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-102932
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MNX1(Accession P50219), corresponding to amino acid residues D361-Q401.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852310
产品详细信息
Antibody detects endogenous levels of total MNX1.
靶标信息
Homeobox protein HB9 is expressed in lymphoid and pancreatic tissues. It is reported to be Putative transcription factor involved in pancreas development and function. Defects in this gene causes Currarino syndrome. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. It is also reported that HB9 is strongly expressed in epidermal basal cells of the outer scale face in tarsometatarsal scale skin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homeobox gene HB9; homeobox HB9; Homeobox protein HB9; HOX SCRA1; Motor neuron and pancreas homeobox 1; Motor neuron and pancreas homeobox protein 1
基因别名: HB9; HLXB9; HOXHB9; MNR2; MNX1; SCRA1
UniProt ID: (Human) P50219, (Rat) M0R6D8
Entrez Gene ID: (Human) 3110, (Rat) 682076, (Mouse) 15285
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
humoral immune response
anatomical structure morphogenesis
spinal cord motor neuron cell fate specification
endocrine pancreas development
neuron projection morphogenesis
neuron migration
regulation of transcription, DNA-templated
motor neuron axon guidance
biological_process
post-embryonic development
nerve development
dorsal/ventral neural tube patterning
central nervous system neuron differentiation
neuron differentiation
pancreas development
cell morphogenesis involved in neuron differentiation
diaphragm development
respiratory system development
