Invitrogen

HCFC1 Polyclonal Antibody

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HCFC1 Antibody (PA5-30222) in WB

Western Blot analysis of HCFC1 was performed by separating 30 µg of A549 whole cell and nuclear extracts by 5% SDS-PAGE. Proteins were transferred to a membrane and probed with a HCFC1 Polyclonal Antibody (Product # PA5-30222) at a dilution of 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

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产品信息

PA5-30222

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

产品规格

种属反应

Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 49 and 269 of Human HCF1

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.76 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 20% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2547696

产品详细信息

Recommended positive controls: HeLa, A549, A549 nuclear extract, rat brain.

Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (94%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins that link the TNF receptor superfamily to signaling pathways and are thus important regulators of cell death and cellular response to stress. TRAF proteins share a homology region that allows them to bind to cell receptors and other TRAF proteins, causing the activation of different signal cascades depending on the TRAFs involved. For example, TRAF2 and TRAF3 directly bind to the CD40, a NF receptor superfamily member involved in inducing B cell immunity, and are critical for NF-kappa-B activation in mouse B lymphocytes. TRAF2 along with TRAF6 has also been shown to be required for CD40 signaling in nonhemopoietic cells. TRAF2 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF3 and the apoptosis inhibitors cIAP1 and Smac.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。