Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-88165
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 178-397 of human DNAJA1 (NP_0015301)
偶联物
形式
Liquid
浓度
1.27 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804707
产品详细信息
Immunogen sequence: MECQGHGERI SPKDRCKSCN GRKIVREKKI LEVHIDKGMK DGQKITFHGE GDQEPGLEPG DIIIVLDQKD HAVFTRRGED LFMCMDIQLV EALCGFQKPI STLDNRTIVI TSHPGQIVKH GDIKCVLNEG MPIYRRPYEK GRLIIEFKVN FPENGFLSPD KLSLLEKLLP ERKEVEETDE MDQVELVDFD PNQERRRHYN GEAYEDDEHH PRGGVQCQTS; Positive Samples: MCF7, HeLa, Jurkat, U-87MG, HepG2, Mouse brain, Mouse kidney, Mouse liver, Rat liver; Cellular Location: Cytoplasm, Lipid-anchor, Membrane, Microsome, Mitochondrion, Nucleus, perinuclear region
靶标信息
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1. 6 kb and a protein product with a molecular weight of about 35 kDa.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: DnaJ (Hsp40) homolog, subfamily A, member 1; DnaJ homolog subfamily A member 1; DnaJ protein homolog 2; h HSJ-2; hDj-2; Heat shock 40 kDa protein 4; Heat shock protein J2; heat shock protein, DNAJ-like 2; HSDJ; HSJ-2; Human DnaJ protein 2; neural precursor cell expressed, developmentally down-regulated 7; neural precursor cell expressed, developmentally down-regulated gene 7
基因别名: DJ-2; DjA1; DNAJ2; DNAJA1; hDJ-2; HDJ2; HSDJ; HSJ-2; HSJ2; HSPF4; NEDD7
UniProt ID: (Human) P31689, (Mouse) P63037
Entrez Gene ID: (Human) 3301, (Mouse) 15502
G-protein coupled receptor binding
protein binding
ATP binding
Hsp70 protein binding
Tat protein binding
ubiquitin protein ligase binding
metal ion binding
low-density lipoprotein particle receptor binding
unfolded protein binding
chaperone binding
C3HC4-type RING finger domain binding
heat shock protein binding
chaperone
protein folding
response to unfolded protein
spermatogenesis
response to heat
sperm motility
androgen receptor signaling pathway
negative regulation of protein ubiquitination
DNA damage response, detection of DNA damage
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of JUN kinase activity
regulation of protein transport
protein localization to mitochondrion
toxin transport
negative regulation of establishment of protein localization to mitochondrion
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
protein refolding
