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HECTD1 Antibody (PA5-103813) in IHC (P)
Immunohistochemistry analysis of HECTD1 in human kidney cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with HECTD1 polyclonal antibody (Product # PA5-103813) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-103813
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human HECTD1(Accession Q9ULT8), corresponding to amino acid residues L618-I668.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853146
产品详细信息
Antibody detects endogenous levels of total HECTD1.
靶标信息
Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ligase for inhibin receptor; E3 ubiquitin-protein ligase HECTD1; EULIR; HECT domain containing 1; HECT domain containing E3 ubiquitin protein ligase 1; HECT domain-containing protein 1; protein open mind
基因别名: A630086P08Rik; AI844876; b2b327Clo; EULIR; HECTD1; KIAA1131; opm; RGD1561653
UniProt ID: (Human) Q86VJ1
Entrez Gene ID: (Human) 25831, (Mouse) 207304, (Rat) 362736
ubiquitin-protein transferase activity
protein binding
ligase activity
metal ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
natural killer cell differentiation
neural tube closure
embryonic placenta development
protein ubiquitination
protein autoubiquitination
trophoblast giant cell differentiation
spongiotrophoblast differentiation
protein K63-linked ubiquitination
negative regulation of protein localization to plasma membrane
