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Product Details
PA5-100761
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human HES3(Accession Q5TGS1), corresponding to amino acid residues R5-G55.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2850264
Product Specific Information
Antibody detects endogenous levels of total HES3.
Target Information
Transcriptional repressor of genes that require a bHLH protein for their transcription. Target protein's helix-loop-helix (HLH) protein; may function as repressor in neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLHb43; Class B basic helix-loop-helix protein 43; Hairy and enhancer of split 3; Transcription factor HES-3
Gene Aliases: BHLHB43; Hes-3; HES3
UniProt ID: (Human) Q5TGS1, (Rat) Q04667, (Mouse) Q61657
Entrez Gene ID: (Human) 390992, (Rat) 64628, (Mouse) 15207
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
transcription, DNA-templated
midbrain-hindbrain boundary morphogenesis
oculomotor nerve development
trochlear nerve development
hindbrain morphogenesis
midbrain development
positive regulation of transcription from RNA polymerase II promoter
regulation of timing of neuron differentiation
neural tube development
negative regulation of transcription, DNA-templated
regulation of neurogenesis
regulation of transcription, DNA-templated
Performance Guarantee
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