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产品信息
PA5-100761
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human HES3(Accession Q5TGS1), corresponding to amino acid residues R5-G55.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2850264
产品详细信息
Antibody detects endogenous levels of total HES3.
靶标信息
Transcriptional repressor of genes that require a bHLH protein for their transcription. Target protein's helix-loop-helix (HLH) protein; may function as repressor in neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLHb43; Class B basic helix-loop-helix protein 43; Hairy and enhancer of split 3; Transcription factor HES-3
基因别名: BHLHB43; Hes-3; HES3
UniProt ID: (Human) Q5TGS1, (Rat) Q04667, (Mouse) Q61657
Entrez Gene ID: (Human) 390992, (Rat) 64628, (Mouse) 15207
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
transcription, DNA-templated
midbrain-hindbrain boundary morphogenesis
oculomotor nerve development
trochlear nerve development
hindbrain morphogenesis
midbrain development
positive regulation of transcription from RNA polymerase II promoter
regulation of timing of neuron differentiation
neural tube development
negative regulation of transcription, DNA-templated
regulation of neurogenesis
regulation of transcription, DNA-templated
