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HEXIM1 Antibody (PA5-104211) in IHC (P)
Immunohistochemistry analysis of HEXIM1 in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with HEXIM1 polyclonal antibody (Product # PA5-104211) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-104211
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human HEXIM1(Accession O94992), corresponding to amino acid residues E326-D359.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853539
产品详细信息
Antibody detects endogenous levels of total HEXIM1.
靶标信息
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cardiac lineage protein 1; Estrogen down-regulated gene 1 protein; FLJ13562; hexamethylene bis-acetamide inducible 1; Hexamethylene bis-acetamide-inducible protein 1; hexamethylene bisacetamide-inducible protein; hexamethylene-bis-acetamide-inducible transcript 1; hexamthylene bis-acetamide inducible 1; HGNC:24953; HMBA-inducible; menage a quatre 1; Menage a quatre protein 1; Protein HEXIM1
基因别名: 7330426E13Rik; CLP-1; CLP1; EDG1; HEXIM1; HIS1; MAQ1
UniProt ID: (Human) O94992, (Mouse) Q8R409, (Rat) Q5M9G1
Entrez Gene ID: (Human) 10614, (Mouse) 192231, (Rat) 498008
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
heart development
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of signal transduction by p53 class mediator
