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产品信息
PA5-17540
产品规格
种属反应
Bovine,
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues surrounding Ala104 of human Hic-5
偶联物
形式
Liquid
浓度
75 µg/mL
纯化类型
Antigen affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10987542
产品详细信息
It is not recommended to aliquot this antibody.
靶标信息
This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Androgen receptor coactivator 55 kDa protein; androgen receptor coactivator ARA55; Androgen receptor-associated protein of 55 kDa; Hic-5; Hydrogen peroxide-inducible clone 5 protein; hydrogen peroxide-inducible clone-5; Transforming growth factor beta-1-induced transcript 1 protein
基因别名: ARA55; BOS_22886; HIC-5; HIC5; TGFB1I1; TSC-5
UniProt ID: (Bovine) Q3MHZ4, (Human) O43294
Entrez Gene ID: (Bovine) 515834, (Human) 7041
positive regulation of epithelial to mesenchymal transition
Wnt signaling pathway
morphogenesis of embryonic epithelium
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
ubiquitin-dependent SMAD protein catabolic process
epithelial cell differentiation
cell fate commitment
negative regulation of fat cell differentiation
transcription from RNA polymerase II promoter
cell adhesion
negative regulation of cell proliferation
response to heat
androgen receptor signaling pathway
positive regulation of transcription, DNA-templated
