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产品信息
PA5-28839
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human HIC5
偶联物
形式
Liquid
浓度
0.79 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546315
产品详细信息
Recommended positive controls: Hic-5 tansfected 293T cell.
Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Androgen receptor coactivator 55 kDa protein; androgen receptor coactivator ARA55; Androgen receptor-associated protein of 55 kDa; Hic-5; Hydrogen peroxide-inducible clone 5 protein; hydrogen peroxide-inducible clone-5; Transforming growth factor beta-1-induced transcript 1 protein
基因别名: ARA55; HIC-5; HIC5; TGFB1I1; TSC-5
UniProt ID: (Human) O43294
Entrez Gene ID: (Human) 7041
transcription from RNA polymerase II promoter
cell adhesion
negative regulation of cell proliferation
response to heat
positive regulation of epithelial to mesenchymal transition
Wnt signaling pathway
morphogenesis of embryonic epithelium
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
androgen receptor signaling pathway
ubiquitin-dependent SMAD protein catabolic process
epithelial cell differentiation
cell fate commitment
negative regulation of fat cell differentiation
positive regulation of transcription, DNA-templated
