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HIP1R Antibody (PA5-30863) in ICC/IF
HIP1 Related antibody [N1N2], N-term detects HIP1R protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: HIP1R protein stained by HIP1 Related antibody [N1N2], N-term (Product # PA5-30863) diluted at 1:500. Blue: Hoechst 33343 staining.
产品信息
PA5-30863
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 14 and 261 of Human HIP1 Related
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548337
产品详细信息
Recommended positive controls: MCF-7.
Predicted reactivity: Mouse (96%), Rat (97%), Xenopus laevis (89%), Rabbit (95%), Chicken (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Huntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HIP-12; HIP1-related protein; huntingtin interacting protein 12; Huntingtin-interacting protein 1-related protein; Huntingtin-interacting protein 12
基因别名: HIP12; HIP1R; HIP3; ILWEQ; KIAA0655
UniProt ID: (Human) O75146
Entrez Gene ID: (Human) 9026, (Rat) 81917
