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HIPK1 Antibody (PA5-115358) in IHC (P)
Immunohistochemistry analysis of HIPK1 in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with HIPK1 polyclonal antibody (Product # PA5-115358) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-115358
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human HIPK1(Accession Q86Z02), corresponding to amino acid residues S9-S59.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2899994
产品详细信息
Antibody detects endogenous levels of total HIPK1.
靶标信息
HIPK1 phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. The protein encoded by HIPK1 belongs to the Ser/Thr family of protein kinases and HIPK subfamily. Alternative splicing results in four transcript variants encoding four distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hipk1 {ECO:0000312|EMBL:ABO47653.1}; homeodomain interacting protein kinase 1-like protein; Homeodomain-interacting protein kinase 1; nuclear body associated kinase 2b; Nuclear body-associated kinase 2; Protein kinase Myak
基因别名: 1110062K04Rik; HIPK1; KIAA0630; MYAK; NBAK2
UniProt ID: (Human) Q86Z02, (Mouse) O88904
Entrez Gene ID: (Human) 204851, (Rat) 365895, (Mouse) 15257
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
smoothened signaling pathway
positive regulation of cell proliferation
anterior/posterior pattern specification
regulation of tumor necrosis factor-mediated signaling pathway
retina layer formation
neuron differentiation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
embryonic camera-type eye morphogenesis
embryonic retina morphogenesis in camera-type eye
lens induction in camera-type eye
iris morphogenesis
endothelial cell apoptotic process
extrinsic apoptotic signaling pathway
negative regulation of transcription from RNA polymerase II promoter
phosphorylation
positive regulation of DNA binding
eye development
adherens junction assembly
positive regulation of angiogenesis
definitive hemopoiesis
regulation of signal transduction by p53 class mediator
