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产品信息
MA5-42602
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6B7Q2
抗原
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Hexokinase 1 (P19367)
偶联物
形式
Liquid
浓度
0.65 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2911743
产品详细信息
Positive test controls include: 293T, MCF7, Mouse testis, Mouse brain, Rat testis, Rat brain. The target is usually found in the following locations: Mitochondrion outer membrane.
Immunogen sequence: GLSRDFNPTA TVKMLPTFVR SIPDGSEKGD FIALDLGGSS FRILRVQVNH EKNQNVHMES EVYDTPENIV HGSGSQLFDH VAECLGDFME KRKIKDKKLP V
靶标信息
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brain form hexokinase; downeast anemia; glycolytic enzyme; hexokinase I; hexokinase IR; Hexokinase type I; Hexokinase, tumor isozyme; Hexokinase-1; Hexokinase-A; HK I
基因别名: BB404130; dea; HEXOKIN; hexokinase; HK; Hk-1; HK1; Hk1-s; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1; mHk1-s
UniProt ID: (Human) P19367, (Rat) P05708, (Mouse) P17710
Entrez Gene ID: (Human) 3098, (Rat) 25058, (Mouse) 15275
glucokinase activity
hexokinase activity
protein binding
ATP binding
glucose binding
fructokinase activity
mannokinase activity
protein kinase activity
ATPase activity
protein complex binding
protein homodimerization activity
nucleotide binding
catalytic activity
kinase activity
transferase activity
phosphotransferase activity, alcohol group as acceptor
kinase
cellular glucose homeostasis
glycolytic process
glucose transport
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
establishment of protein localization to mitochondrion
maintenance of protein location in mitochondrion
response to ischemia
protein phosphorylation
regulation of anion channel activity
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
hexose metabolic process
negative regulation of apoptotic process
protein autophosphorylation
carbohydrate metabolic process
metabolic process
phosphorylation
