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产品信息
PA5-121197
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human HK3 (NP_002106.2).
偶联物
形式
Liquid
浓度
0.83 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914769
产品详细信息
Positive test controls include: HepG2, HL-60, THP-1, NCI-H460, Mouse liver.
Immunogen sequence: MDSIGSSGLR QGEETLSCSE EGLPGPSDSS ELVQECLQQF KVTRAQLQQI QASLLGSMEQ ALRGQASPAP AVRMLPTYVG STPHGTEQGD FVVLELGATG ASLRVLWVTL TGIEGHRVEP RSQEFVIPQE VMLGAGQQLF DFAAHCLSEF LDAQPVNKQG LQLGFSFSFP CHQTGLDRST LISWTKGFRC SGVEGQDVVQ LLRDAIRRQG AYNIDVVAVV NDTVGTMMGC EPGVRPCEVG LVVDTGTNAC YMEEARHVAV LDEDRGRVCV
靶标信息
Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. In vertebrates there are four major glucose phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product glucose 6 phosphate. The catalytic activity of hexokinase III is associated with the C terminus while regulatory function is associated with the N terminus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP:D-hexose 6-phosphotransferase; hexokinase 3 (white cell); hexokinase iii; Hexokinase type III; Hexokinase-3; Hexokinase-C; Hexokinase3; HK III
基因别名: HK III; HK-III; HK3; HKIII; HXK3; RNU73859
UniProt ID: (Human) P52790, (Rat) P27926, (Mouse) Q3TRM8
Entrez Gene ID: (Human) 3101, (Rat) 25060, (Mouse) 212032
cellular glucose homeostasis
glycolytic process
glucose transport
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
biological_process
hexose metabolic process
carbohydrate metabolic process
metabolic process
phosphorylation
negative regulation of hydrogen peroxide-mediated programmed cell death
