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HOXA1 Antibody (PA5-68809) in WB
Western blot was performed using Anti-HOXA1 Polyclonal Antibody (Product # PA5-68809) and a 36 kDa band corresponding to HOXA1 was observed in Mouse and Rat Brain but not in Mouse Lung and Rat Lung. Hoxa1 target gene is involved in the development of the nervous system and/or brain development. Tissue extracts (30 µg lysate) of Mouse Brain (Lane 1), Rat Brain (Lane 2), Mouse Lung (Lane 3) and Rat Lung (Lane 4) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0322BOX). Resolved proteins were then transferred onto a... View More
Product Details
PA5-68809
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the c terminal region of mouse HOXA1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2688732
Product Specific Information
This target displays homology in the following species: Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 86%; Mouse: 100%; Rabbit: 86%; Rat: 100%
Target Information
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: early retinoic acid 1; homeo box A1; homeobox protein Hox-1.6; homeobox protein Hox-A1; homeoboxless protein ERA-1-399; homeotic protein ERA-1-993; HOXA 1; HOXA-1; MGC45232
Gene Aliases: ERA1; Hox-1.6
Entrez Gene ID: (Mouse) 15394
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
nervous system development
sensory perception of sound
optokinetic behavior
motor neuron axon guidance
anatomical structure morphogenesis
anterior/posterior pattern specification
rhombomere 3 development
rhombomere 4 development
rhombomere 5 development
abducens nerve formation
facial nerve structural organization
facial nucleus development
central nervous system neuron differentiation
hindbrain development
inner ear morphogenesis
outer ear morphogenesis
positive regulation of transcription from RNA polymerase II promoter
anatomical structure formation involved in morphogenesis
embryonic neurocranium morphogenesis
inner ear development
artery morphogenesis
regulation of behavior
cognition
neuromuscular process
artery development
semicircular canal formation
cellular response to retinoic acid
cochlea development
cochlea morphogenesis
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