Invitrogen

HOXB4 Monoclonal Antibody (3A2F2)

HOXB4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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HOXB4 Antibody (MA5-31768) in IHC (P)

Immunohistochemistry analysis of HOXB4 in paraffin-embedded rectum cancer tissue. Sample was incubated with HOXB4 monoclonal antibody (Product # MA5-31768) using a dilution of 1:200-1:1000 followed by DAB staining.

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产品信息

MA5-31768

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:200-1:1,000

酶联免疫吸附实验 (ELISA)

1:10,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

3A2F2

抗原

Purified recombinant fragment of human HOXB4 (AA: 16-251) expressed in E. coli.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein G

保存液

PBS

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2787391

产品详细信息

MA5-31768 has been tested in indirect ELISA.

靶标信息

HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。