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产品信息
PA5-40577
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human HOXC11
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2610292
产品详细信息
Peptide sequence: DRFFDNAYCG GGDPPAEPPC SGKGEAKGEP EAPPASGLAS RAEAGAEAEA
Sequence homology: Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
靶标信息
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homeo box C11; Homeobox protein Hox-3.7; Homeobox protein Hox-3H; Homeobox protein Hox-C11; MGC4906
基因别名: Hox-3.7; HOX3H; Hoxc-11; HOXC11
UniProt ID: (Human) O43248, (Mouse) P31313
Entrez Gene ID: (Human) 3227, (Mouse) 109663
metanephros development
organ induction
transcription from RNA polymerase II promoter
endoderm development
anterior/posterior pattern specification
proximal/distal pattern formation
embryonic digit morphogenesis
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal joint morphogenesis
skeletal system development
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
