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At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Antigen p25; chromobox homolog 1; chromobox homolog 1 (HP1 beta homolog Drosophila ); chromobox homolog 3; chromobox homolog 3 (HP1 gamma homolog, Drosophila); chromobox homolog 5; chromobox homolog 5 (HP1 alpha homolog, Drosophila); Chromobox protein homolog 1; Chromobox protein homolog 3; Chromobox protein homolog 5; epididymis luminal protein 25; HECH; heterochromatin protein 1 alpha; heterochromatin protein 1 gamma; Heterochromatin protein 1 homolog alpha; Heterochromatin protein 1 homolog beta; Heterochromatin protein 1 homolog gamma; heterochromatin protein 1-alpha; heterochromatin protein 1-beta; heterochromatin protein HP1 gamma; Heterochromatin protein p25; heterochromatin protein p25 beta; heterochromatin-like protein 1; HP1 alpha; HP1 alpha homolog; HP1 beta; HP1 beta homolog; HP1 gamma; HP1 gamma homolog; HP1-ALPHA; HP1Hs alpha; HP1Hsbeta; M31; mHP1(alpha); Modifier 1 protein; Modifier 2 protein; p25beta
基因别名: 2610029O15Rik; C75991; CBX; Cbx-rs2; CBX1; CBX3; CBX5; E430007M08Rik; HECH; HEL25; HP1; HP1-BETA; HP1-GAMMA; HP1A; Hp1alpha; HP1B; Hp1beta; HP1g; HP1Hs-beta; HP1Hs-gamma; HP1Hsbeta; M31; M32; MOD1; p25beta
UniProt ID: (Human) P83916, (Human) Q13185, (Human) P45973, (Mouse) P83917, (Mouse) Q61686
Entrez Gene ID: (Human) 10951, (Human) 11335, (Human) 23468, (Mouse) 12412, (Mouse) 12417, (Mouse) 12419