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产品信息
PA5-58343
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2642533
产品详细信息
Immunogen sequence: REPWVEQDKF GKVKFAVLQT YGDTTHTLVE KMNYIGQFLP GYEAPAFMDP LLPKLPKCSL EMIDHIVGNQ P
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 83%.
靶标信息
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity (1-3). Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli. This protein called Omi/HtrA2 is a mitochondrial protein that binds to IAP (4). Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis indicating that Omi could participate in the mitochondrial apoptotic pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4-H HPPDASE; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4H GLOD3; 4HPPD; F Alloantigen; F liver antigen; F protein; glyoxalase domain containing 3; HPPDase
基因别名: 4-HPPD; 4HPPD; Fla; Flp; GLOD3; HPD; Hppd; HPPDASE; Laf; PPD
UniProt ID: (Human) P32754, (Mouse) P49429, (Rat) P32755
Entrez Gene ID: (Human) 3242, (Mouse) 15445, (Rat) 29531
