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产品信息
MA5-32797
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat,
Zebrafish
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JU03-26
抗原
Synthetic peptide within Human HPRT aa 169-218
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2810073
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
The protein is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HGPRT; HGPRTase; HPRT 1; HPRT B; hypoxanthine guanine phosphoribosyl transferase 1; hypoxanthine phosphoribosyl transferase; Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 1; testicular tissue protein Li 89
基因别名: C81579; HGPRT; Hgprtase; HPGRT; HPRT; HPRT1; id:ibd1344; id:ibd5108; wu:fc10g09; zgc:56221; zgc:86608
UniProt ID: (Human) P00492, (Mouse) P00493, (Rat) P27605
Entrez Gene ID: (Human) 3251, (Mouse) 15452, (Rat) 24465, (Zebrafish) 406259
nucleotide binding
magnesium ion binding
hypoxanthine phosphoribosyltransferase activity
protein binding
protein homodimerization activity
guanine phosphoribosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
identical protein binding
metal ion binding
glycosyltransferase
response to amphetamine
purine nucleotide biosynthetic process
purine ribonucleoside salvage
adenine salvage
guanine salvage
grooming behavior
locomotory behavior
cytolysis
striatum development
cerebral cortex neuron differentiation
central nervous system neuron development
GMP salvage
IMP salvage
dopamine metabolic process
purine-containing compound salvage
hypoxanthine salvage
positive regulation of dopamine metabolic process
GMP catabolic process
IMP metabolic process
hypoxanthine metabolic process
lymphocyte proliferation
dendrite morphogenesis
protein homotetramerization
nucleoside metabolic process
adenine metabolic process
spermatogenesis
brain development
cellular response to insulin stimulus
