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HPa2 Antibody (PA5-121181) in IHC (P)
Immunohistochemistry analysis of HPa2 in paraffin-embedded human prostate. Samples were incubated with HPa2 Polyclonal antibody (Product # PA5-121181) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-121181
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 42-242 of human HPSE2 (NP_068600.4).
Conjugate
Form
Liquid
Concentration
1.67 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914753
Product Specific Information
Positive test controls include: BT-474, 22Rv1, HeLa, SKOV3, Mouse brain, Mouse small intestine, Mouse testis, Mouse uterus, Rat brain. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.
Immunogen sequence: GDRRPLPVDR AAGLKEKTLI LLDVSTKNPV RTVNENFLSL QLDPSIIHDG WLDFLSSKRL VTLARGLSPA FLRFGGKRTD FLQFQNLRNP AKSRGGPGPD YYLKNYEDDI VRSDVALDKQ KGCKIAQHPD VMLELQREKA AQMHLVLLKE QFSNTYSNLI LTARSLDKLY NFADCSGLHL IFALNALRRN PNNSWNSSSA L
Target Information
This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: heparanase 3; heparanase-2; heparanase-like protein; Hpa2; Inactive heparanase-2
Gene Aliases: Gm968; HPA2; HPR2; HPSE2; UFS; UFS1
UniProt ID: (Human) Q8WWQ2, (Mouse) B2RY83
Entrez Gene ID: (Human) 60495, (Mouse) 545291, (Rat) 368128
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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