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Positive test controls include: BT-474, 22Rv1, HeLa, SKOV3, Mouse brain, Mouse small intestine, Mouse testis, Mouse uterus, Rat brain. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.
Immunogen sequence: GDRRPLPVDR AAGLKEKTLI LLDVSTKNPV RTVNENFLSL QLDPSIIHDG WLDFLSSKRL VTLARGLSPA FLRFGGKRTD FLQFQNLRNP AKSRGGPGPD YYLKNYEDDI VRSDVALDKQ KGCKIAQHPD VMLELQREKA AQMHLVLLKE QFSNTYSNLI LTARSLDKLY NFADCSGLHL IFALNALRRN PNNSWNSSSA L
This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: heparanase 3; heparanase-2; heparanase-like protein; Hpa2; Inactive heparanase-2
基因别名: Gm968; HPA2; HPR2; HPSE2; UFS; UFS1
UniProt ID: (Human) Q8WWQ2, (Mouse) B2RY83
Entrez Gene ID: (Human) 60495, (Mouse) 545291, (Rat) 368128