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This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: heparanase 3; heparanase-like protein; Hpa2; Inactive heparanase-2
基因别名: HPA2; HPR2; HPSE2; UFS; UFS1
UniProt ID: (Human) Q8WWQ2
Entrez Gene ID: (Human) 60495