Invitrogen

HRC Polyclonal Antibody

抗体检测数据 (4)
高级验证 (1)

HRC Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HRC Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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HRC Antibody (PA5-52120) in IHC (P)

Immunohistochemical analysis of HRC in human heart muscle using HRC Polyclonal Antibody (Product # PA5-52120) shows high expression.

HRC Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HRC Antibody in Immunohistochemistry (IHC)

HRC Antibody in Immunohistochemistry (IHC)

HRC Antibody in Western Blot (WB)

Product Image Gallery

HRC Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of HRC in human heart muscle using HRC Polyclonal Antibody (Product # PA5-52120) shows high expression.

HRC Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of HRC in human heart muscle and skin tissues using HRC Polyclonal Antibody (Product # PA5-52120). Corresponding HRC RNA-seq data are presented for the same tissues.

HRC Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of HRC in human skin using HRC Polyclonal Antibody (Product # PA5-52120) shows low expression as expected.

HRC Antibody in Western Blot (WB) — Western blot analysis of HRC in human heart tissue using a HRC Polyclonal Antibody (Product # PA5-52120).

HRC Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of HRC demonstrates antibody specificity. Immunohistochemical analysis of HRC using anti-HRC Polyclonal Antibody (Product # PA5-52120), shows significant staining of HRC in human heart muscle and shows minimal or weak staining in human skin tissues. The relative expression levels of HRC within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-52120

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

-

免疫组化（石蜡） (IHC (P))

1:1,000-1:2,500

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human HRC. Recombinant protein control fragment (Product #RP-102410).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2642540

产品详细信息

Immunogen sequence: SHEEDDNDDD DVSTEYGHQA HRHQDHRKEE VEAVSGEHHH HVPDHRHQGH RDEEEDEDVS TERWHQGPQH VHHGLVDEEE EEEEITVQFG HYVASHQPRG HKSDEEDFQD EYKTEVPHHH HHRVPREEDE EVSAELG

Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 51%.

靶标信息

May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Sarcoplasmic reticulum histidine-rich calcium-binding protein

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基因别名: HCP; HRC

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UniProt ID: (Human) P23327

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Entrez Gene ID: (Human) 3270

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calcium ion binding protein binding ion channel binding ATPase binding

regulation of heart rate muscle contraction positive regulation of heart rate regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion regulation of peptidyl-serine phosphorylation positive regulation of heart contraction regulation of cytosolic calcium ion concentration negative regulation of cytosolic calcium ion concentration regulation of ryanodine-sensitive calcium-release channel activity regulation of cell communication by electrical coupling involved in cardiac conduction positive regulation of relaxation of cardiac muscle regulation of calcium ion transmembrane transport