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HSD17B3 Antibody (PA5-30063) in ICC/IF
HSD17B3 Polyclonal Antibody detects HSD17B3 protein at cytoplasm by confocal immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: HSD17B3 protein stained by HSD17B3 Polyclonal Antibody (Product # PA5-30063) diluted at 1:500. Blue: Hoechst 33342 staining. [Images captured by Olympus FV10i Confocal Laser Scanning Microscope].
产品信息
PA5-30063
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 122 and 310 of Human HSD17B3
偶联物
形式
Liquid
浓度
0.44 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547537
产品详细信息
Recommended positive controls: Raji.
Predicted reactivity: Pig (81%), Rhesus Monkey (97%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 17(beta)HSD type 3; 17-beta-HSD 3; 17-beta-HSD3; 17-beta-hydroxysteroid dehydrogenase type 3; 17beta-HSD; estradiol 17 beta-dehydrogenase 3; Estradiol 17-beta-dehydrogenase 2; hydroxysteroid (17-beta) dehydrogenase 3; hydroxysteroid dehydrogenase 3; Short chain dehydrogenase/reductase family 12C member 2; short chain dehydrogenase/reductase family 12C, member 2; Testicular 17-beta-hydroxysteroid dehydrogenase; Testosterone 17-beta-dehydrogenase 3
基因别名: EDH17B3; HSD17B3; SDR12C2
UniProt ID: (Human) P37058, (Mouse) P70385, (Rat) O54939
Entrez Gene ID: (Human) 3293, (Mouse) 15487, (Rat) 117182
lipid metabolic process
steroid biosynthetic process
metabolic process
oxidation-reduction process
organic acid metabolic process
response to herbicide
response to metal ion
response to lead ion
response to organic cyclic compound
response to activity
response to insecticide
insecticide metabolic process
biphenyl metabolic process
phenol-containing compound metabolic process
hippocampus development
response to nutrient levels
cellular response to hormone stimulus
response to vitamin E
Leydig cell differentiation
response to L-ascorbic acid
response to estrogen
response to ethanol
response to arsenic-containing substance
response to cadmium ion
response to steroid hormone
response to corticosterone
response to fungicide
testosterone biosynthetic process
response to fatty acid
cellular response to antibiotic
cellular response to gonadotropin stimulus
androgen biosynthetic process
male genitalia development
