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产品信息
PA5-88882
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human HSD17B8 (NP_0550491)
偶联物
形式
Liquid
浓度
1.16 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805193
产品详细信息
Immunogen sequence: MASQLQNRLR SALALVTGAG SGIGRAVSVR LAGEGATVAA CDLDRAAAQE TVRLLGGPGS KEGPPRGNHA AFQADVSEAR AARCLLEQVQ ACFSRPPSVV VSCAGITQDE FLLHMSEDDW DKVIAVNLKG TFLVTQAAAQ ALVSNGCRGS IINISSIVGK VGNVGQTNYA ASKAGVIGLT QTAARELGRH GIRCNSVLPG FIATPMTQKV PQKVVDKITE MIPMGHLGDP EDVADVVAFL ASEDSGYITG TSVEVTGGLF M; Positive Samples: HepG2, BxPC3, U87, HeLa, Mouse liver, Rat pancreas, Rat heart; Cellular Location: Mitochondrion matrix
靶标信息
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-HSD 8; 17-beta-hydroxysteroid dehydrogenase 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; estrogen 17-oxidoreductase; H FABGL; hydroxysteroid (17-beta) dehydrogenase 8; KAR alpha subunit; ke-6; Ke6; Protein Ke6; really interesting new gene 2 protein; Short chain dehydrogenase/reductase family 30C member 1; short chain dehydrogenase/reductase family 30C, member 1; Testosterone 17-beta-dehydrogenase 8
基因别名: D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; HSD17B8; KE6; RING2; SDR30C1
UniProt ID: (Human) Q92506, (Rat) Q6MGB5
Entrez Gene ID: (Human) 7923, (Rat) 361802
