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产品信息
MA5-32408
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
SD85-06
抗原
Recombinant protein within Human Hsp105 aa 17-117
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2809686
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. This protein inhibits HSPA8/HSC70 ATPase and chaperone activities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 42 degrees C-HSP; Antigen NY-CO-25; heat shock 105kD alpha; heat shock 105kD beta; heat shock 105kDa; heat shock 105kDa/110kDa protein 1; Heat shock 110 kDa protein; Heat shock protein; Heat shock protein 105 kDa; heat shock protein 110; Heat shock protein family H member 1; heat shock protein, 105 kDa; Heat shock-related 100 kDa protein E7I; HSP; HSP-E7I; HSP105 42 C-HSP; NY CO 25
基因别名: 105kDa; AI790491; hsp-E7I; HSP105; HSP105A; HSP105B; HSP110; hsp110/105; HSPH1; KIAA0201; NY-CO-25
UniProt ID: (Human) Q92598, (Mouse) Q61699, (Rat) Q66HA8
Entrez Gene ID: (Human) 10808, (Mouse) 15505, (Rat) 288444
response to unfolded protein
negative regulation of neuron apoptotic process
positive regulation of MHC class I biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
chaperone mediated protein folding requiring cofactor
positive regulation of NK T cell activation
positive regulation of protein tyrosine kinase activity
regulation of microtubule cytoskeleton organization
negative regulation of establishment of protein localization to mitochondrion
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
negative regulation of p38MAPK cascade
negative regulation of apoptotic signaling pathway
receptor-mediated endocytosis
regulation of cellular response to heat
