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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Heat shock 70 kDa protein 14; heat shock 70kDa protein 14; heat shock 70kDa protein 14 isoform 1 variant 3; Heat shock protein; heat shock protein 4; Heat shock protein family A member 14; Heat shock protein HSP60; heat shock protein hsp70-related protein; heat shock protein, 70 kDa 4; HSP; HSP70-like protein 1; HSP7E; hsr.1; NST-1
基因别名: 70kDa; HSP60; HSP70-4; HSP70L1; HSPA14; hsr.1; NST-1
UniProt ID: (Human) Q0VDF9, (Mouse) Q99M31
Entrez Gene ID: (Human) 51182, (Mouse) 50497