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Invitrogen
HSPA14 Recombinant Rabbit Monoclonal Antibody (SD08-48)
FIGURE: 1 / 8
HSPA14 Antibody (MA5-32413) in ICC/IF
Immunocytochemical analysis of HSPA14 in RH-35 cells using a HSPA14 Monoclonal antibody (Product # MA5-32413) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Product Details
MA5-32413
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SD08-48
Immunogen
Synthetic peptide within Human HSPA14 aa 51-100
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2809691
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Heat shock 70 kDa protein 14; heat shock 70kDa protein 14; heat shock 70kDa protein 14 isoform 1 variant 3; Heat shock protein; heat shock protein 4; Heat shock protein family A member 14; Heat shock protein HSP60; heat shock protein hsp70-related protein; heat shock protein, 70 kDa 4; HSP; HSP70-like protein 1; HSP7E; hsr.1; NST-1
Gene Aliases: 70kDa; HSP60; HSP70-4; HSP70L1; HSPA14; hsr.1; NST-1
UniProt ID: (Human) Q0VDF9, (Mouse) Q99M31, (Rat) Q6AYB4
Entrez Gene ID: (Human) 51182, (Mouse) 50497, (Rat) 307133
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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