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HTR1A Antibody (PA5-99483) in ICC/IF
Immunofluorescent analysis of HTR1A in HepG2 cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and HTR1A polyclonal antibody (Product # PA5-99483) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-99483
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human HTR1A(Accession P08908), corresponding to amino acid residues S301-M351.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2818416
产品详细信息
Antibody detects endogenous levels of total 5HT1A Receptor.
靶标信息
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5-HT-1A; 5-HT1A; 5-HT1A receptor; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; 5-hydroxytryptamine receptor 1A; G-21; G-protein coupled receptor 18; guanine nucleotide-binding regulatory protein-coupled receptor; Serotonin receptor 1A
基因别名: 5-HT-1A; 5-HT1A; 5HT1A; ADRB2RL1; ADRBRL1; G-21; Gpcr18; HTR1A; PFMCD; RAT5HT1A
UniProt ID: (Human) P08908, (Mouse) Q64264, (Rat) P19327
Entrez Gene ID: (Human) 3350, (Mouse) 15550, (Rat) 24473
behavioral fear response
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting serotonin receptor signaling pathway
serotonin receptor signaling pathway
cell proliferation
positive regulation of cell proliferation
regulation of serotonin secretion
exploration behavior
regulation of dopamine metabolic process
vasoconstriction
serotonin metabolic process
regulation of hormone secretion
regulation of behavior
signal transduction
behavior
positive regulation of microtubule depolymerization
regulation of feeding behavior
NMDA glutamate receptor clustering
