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HTR2B Antibody (PA5-85605) in WB
Western Blot using HTR2B Polyclonal Antibody (Product # PA5-85605). Boiled and unboiled SH-SY5Y cell extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with HTR2B Polyclonal Antibody (Product # PA5-85605) diluted at 1:1,000. (WCE: whole cell extract; ME: membrane extract).
产品信息
PA5-85605
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human 5-HT2B receptor.
偶联物
形式
Liquid
浓度
2.29 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792745
产品详细信息
Keep as concentrated solution.
Positive Control: SH-SY5Y, SH-SY5Y membrane fraction extract, unboiled SH-SY5Y, unboiled SH-SY5Y membrane fraction extract, mouse liver.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
HTR2B is a g-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. HTR2B also plays a role in perception of pain, regulation of behavior. It is required to normal proliferation of embryonic cardiac myocytes and normal heart development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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