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Antibody detects endogenous levels of total HUS1B.
HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.
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蛋白别名: Checkpoint protein HUS1B; hHUS1B; HUS1 checkpoint homolog b; MGC126746; MGC126748; RP11-532F6.1
基因别名: HUS1B
UniProt ID: (Human) Q8NHY5
Entrez Gene ID: (Human) 135458, (Rat) 691382