Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-37443
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 51-100 of human Hairless
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2554064
产品详细信息
This antibody detects endogenous protein at a molecular weight of 127 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
Drosophila genes can be categorized based on the type of protein for which they encode and are represented by six major classifications, which include intracellular signaling proteins, transmembrane proteins, RNA binding proteins, secreted factors, transcription regulators (basic helix-loop-helix, homeodomain containing, zinc finger containing and chromatin associated) or other functional proteins. Among these numerous proteins, Hairless (CG5460, CT36411, CT17282) is a transcriptional co-repressor that contains a "Paired box" domain, a KX-repeat domain, a NEDL-repeat domain and a serine-rich domain. Hairless is an antagonist of the Notch signaling pathway in Drosophila.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: [histone H3]-dimethyl-L-lysine(9) demethylase hairless; HAIR; hairless homolog; Hairless protein; Lysine-specific demethylase hairless; protein hairless
基因别名: ALUNC; AU; ba; bldy; HR; HSA277165; HYPT4; MUHH; MUHH1; N; rh; rh-bmh; rhino
UniProt ID: (Human) O43593, (Mouse) Q61645
Entrez Gene ID: (Human) 55806, (Mouse) 15460, (Rat) 60563
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
oxidoreductase activity
vitamin D receptor binding
histone deacetylase binding
metal ion binding
thyroid hormone receptor binding
sulfonate dioxygenase activity
protein binding
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
histone modifying enzyme
transcription, DNA-templated
regulation of transcription, DNA-templated
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
protein heterooligomerization
oxidation-reduction process
negative regulation of nucleic acid-templated transcription
