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Positive Samples: MCF7, HT-29, Mouse testis; Cellular Location: Endoplasmic reticulum, Microsome
Immunogen sequence: MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA GSTLARETLE DGFPVHDGKG DMRKCPFYAA
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: heme oxygenase (decycling) 2; Heme oxygenase 2; heme oxygenase-2 non-reducing isoform; HMOX 2; HO 2; HO-2
基因别名: HMOX2; HO-2; HO2
UniProt ID: (Human) P30519, (Rat) P23711, (Mouse) O70252
Entrez Gene ID: (Human) 3163, (Rat) 79239, (Mouse) 15369