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Product Details
PA5-34799
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 151 and 438 of Hemopexin (Uniprot ID#P02790)
Conjugate
Form
Liquid
Concentration
0.44 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2552151
Product Specific Information
Recommended positive controls: Target recombinant protein.
Predicted reactivity: Rabbit (81%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Hemopexin is a serum glycoprotein that binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Structurally, hemopexin consists of two similar halves of approximately two hundred amino acid residues connected by a histidine-rich hinge region. Each half is itself formed by the repetition of a basic unit of some 35 to 45 residues.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-1B-glycoprotein; Hemopexin
Gene Aliases: HPX; HX
UniProt ID: (Human) P02790
Entrez Gene ID: (Human) 3263
positive regulation of immunoglobulin production
positive regulation of humoral immune response mediated by circulating immunoglobulin
cellular iron ion homeostasis
receptor-mediated endocytosis
heme transport
viral process
hemoglobin metabolic process
heme metabolic process
positive regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of interferon-gamma-mediated signaling pathway
Performance Guarantee
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