Osenses

Hepcidin Polyclonal Antibody

产品信息

OSH00014W-100UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:2,000

免疫组化 (IHC)

1:100-1:2,000

其他PubMed (Misc)

查看5篇已发表文章 5篇已发表文章

产品规格

种属反应

Human

已发表种属

Not Applicable

宿主/亚型

Rabbit / Ig

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide from mature region of human Hepcidin (HAMP) conjugated to an immunogenic carrier protein has been used as the antigen

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

Conc. Not Determined

保存液

whole serum

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: Hepcidin.

靶标信息

HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The DNA sequence and biology of human chromosome 19.

Nature

Grimwood J,Gordon LA,Olsen A,Terry A,Schmutz J,Lamerdin J,Hellsten U,Goodstein D,Couronne O,Tran-Gyamfi M,Aerts A,Altherr M,Ashworth L,Bajorek E,Black S,Branscomb E,Caenepeel S,Carrano A,Caoile C,Chan YM,Christensen M,Cleland CA,Copeland A,Dalin E,Dehal P,Denys M,Detter JC,Escobar J,Flowers D,Fotopulos D,Garcia C,Georgescu AM,Glavina T,Gomez M,Gonzales E,Groza M,Hammon N,Hawkins T,Haydu L,Ho I,Huang W,Israni S,Jett J,Kadner K,Kimball H,Kobayashi A,Larionov V,Leem SH,Lopez F,Lou Y,Lowry S,Malfatti S,Martinez D,McCready P,Medina C,Morgan J,Nelson K,Nolan M,Ovcharenko I,Pitluck S,Pollard M,Popkie AP,Predki P,Quan G,Ramirez L,Rash S,Retterer J,Rodriguez A,Rogers S,Salamov A,Salazar A,She X,Smith D,Slezak T,Solovyev V,Thayer N,Tice H,Tsai M,Ustaszewska A,Vo N,Wagner M,Wheeler J,Wu K,Xie G,Yang J,Dubchak I,Furey TS,DeJong P,Dickson M,Gordon D,Eichler EE,Pennacchio LA,Richardson P,Stubbs L,Rokhsar DS,Myers RM,Rubin EM,Lucas SM

Thu Apr 01 00:00:00 UTC 2004

A homozygous HAMP mutation in a multiply consanguineous family with pseudo-dominant juvenile hemochromatosis.

Clinical genetics

Delatycki MB,Allen KJ,Gow P,MacFarlane J,Radomski C,Thompson J,Hayden MR,Goldberg YP,Samuels ME

Sat May 01 00:00:00 UTC 2004

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

Genome research

Clark HF,Gurney AL,Abaya E,Baker K,Baldwin D,Brush J,Chen J,Chow B,Chui C,Crowley C,Currell B,Deuel B,Dowd P,Eaton D,Foster J,Grimaldi C,Gu Q,Hass PE,Heldens S,Huang A,Kim HS,Klimowski L,Jin Y,Johnson S,Lee J,Lewis L,Liao D,Mark M,Robbie E,Sanchez C,Schoenfeld J,Seshagiri S,Simmons L,Singh J,Smith V,Stinson J,Vagts A,Vandlen R,Watanabe C,Wieand D,Woods K,Xie MH,Yansura D,Yi S,Yu G,Yuan J,Zhang M,Zhang Z,Goddard A,Wood WI,Godowski P,Gray A