Alomone Labs, LTD

Histamine H2 Receptor (HRH2) (extracellular) Polyclonal Antibody

Histamine H2 Receptor (HRH2) (extracellular) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Histamine H2 Receptor (HRH2) (extracellular) Antibody (AHR-002-200UL) in IHC (P)

Expression of Histamine H2 receptor in rat stomach - Immunohistochemical staining of paraffin embedded section of rat stomach using Anti-Histamine H2Receptor (HRH2) (extracellular) Antibody (#AHR-002), (1:100). H2R (brown staining) is expressed in parietal cells (arrows) of the gastric glands. Hematoxilin is used as the counterstain.

Histamine H2 Receptor (HRH2) (extracellular) Antibody in Western Blot (WB)

Histamine H2 Receptor (HRH2) (extracellular) Antibody in Flow Cytometry (Flow)

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产品信息

AHR-002-200UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

免疫组化（石蜡） (IHC (P))

1:100

流式细胞分析 (Flow)

1:20

产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

RNGTRGGNDTFKC, corresponding to amino acids 161-173 of rat HRH2, 2nd extracellular loop

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.8 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

靶标信息

H2 Histamine Receptor stimulates adenylate cyclase activity and leads to the release of acids in the stomach. It is also involved in GI motility and intestinal secretion. Treatments for acid-peptic disorders are based on the inhibition of histamine H2 receptor activity. The 3-untranslated region may be involved in differential expression. Histamine H2 receptor has been reported to be expressed in bone marrow, brain, heart, lymph node, nose, placenta, spinal cord, and stomach. An EST has been isolated from a kidney library.

仅用于科研。不用于诊断过程。未经明确授权不得转售。