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Homer2 Antibody (APZ-027-200UL) in IHC (F)
Expression of Homer2 in mouse cerebellum and rat hippocampus - Immunohistochemical staining of perfusion-fixed frozen mouse and rat brain sections with Anti-Homer2 Antibody (#APZ-027), (1:200), followed by goat- Anti-rabbit-AlexaFluor-488. A. Homer2 staining (green) in mouse cerebellum is observed in Purkinje cells (arrows) and their dendrites. B. Homer2 staining (green) in rat hippocampal dentate gyrus reg... View More
Product Details
APZ-027-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)EDKVRSLKTDIEESK, corresponding to amino acid residues 302-316 of rat Homer2, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A VESL-2; Cupidin; homer homolog 2; homer homolog 3; Homer protein homolog 2; homer, neuronal immediate early gene, 2; Homer-2; VASP/Ena-related gene up-regulated during seizure and LTP 2; Vesl-2
Gene Aliases: 9330120H11Rik; ACPD; AW539445; CPD; DFNA68; HOMER-2; HOMER2; VESL-2; Vesl2
UniProt ID: (Human) Q9NSB8, (Mouse) Q9QWW1, (Rat) O88801
Entrez Gene ID: (Human) 9455, (Mouse) 26557, (Rat) 29547
G-protein coupled glutamate receptor signaling pathway
sensory perception of sound
regulation of G-protein coupled receptor protein signaling pathway
calcium-mediated signaling using intracellular calcium source
behavioral response to cocaine
chemical homeostasis within a tissue
regulation of store-operated calcium entry
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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