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产品信息
H00003376-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IARS (AAH65552.1, 1 a.a. approximately 1055 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MESVWWVFKQ LYDKGLVYRG VKVMPFSTAC NTPLSNFESH QNYKDVQDPS VFVTFPLEED ETVSLVAWTT TPWTLPSNLA VCVNPEMQYV KIKDVARGRL LILMEARLSA LYKLESDYEI LERFPGAYLK GKKYRPLFDY FLKCKENGAF TVLVDNYVKE EEGTGVVHQA PYFGAEDYRV CMDFNIIRKD SLPVCPVDAS GCFTTEVTDF AGQYVKDADK SIIRTLKEQG RLLVATTFTH SYPFCWRSDT PLIYKAVPSW FVRVENMVDQ LLRNNDLCYW VPELVREKRF GNWLKDARDW TISRNRYWGT PIPLWVSDDF EEVVCIGSVA ELEELSGAKI SDLHRESVDH LTIPSRCGKG SLHRISEVFD CWFESGSMPY AQVHYPFENK REFEDAFPAD FIAEGIDQTR GWFYTLLVLA TALFGQPPFK NVIVNGLVLA SDGQKMSKRK KNYPDPVSII QKYGADALRL YLINSPVVRA ENLRFKEEGV RDVLKDVLLP WYNAYRFLIQ NVLRLQKEEE IEFLYNENTV RESPNITDRW ILSFMQSLIG FFETEMAAYR LYTVVPRLVK FVDILTNWYV RMNRRRLKGE NGMEDCVMAL ETLFSVLLSL CRLMAPYTPF LTELMYQNLK VLIDPVSVQD KDTLSIHYLM LPRVREELID KKTESAVSQM QSVIELGRVI RDRKTIPIKY PLKEIVVIHQ DPEALKDIKS LEKYIIEELN VRKVTLSTDK NKYGIRLRAE PDHMVLGKRL KGAFKAVMTS IKQLSSEELE QFQKTGTIVA EGHELHDEDI RLMYTFDQAT GGTAQFEAHS DAQALVLLDV TPDQSMVDEG MAREVINRIQ KLRKKCNLVP TDEITVYYKA KSEGTYLNSV IESHTEFIFT TIKAPLKPYP VSPSDKVLIQ EKTQLKGSEL EITLTRGSSL PGPACAYVNL NICANGSEQG GVLLLENPKG SAPSLINSSS TLLCQYINLQ LLNAKPQECL MGTVGTLLLE NPLGQNGLTH QGLLYEAAKV FGLRSRKLKL FLNETQTQEI TEDIPVKTLN MKTVYVSVLP TTADF
靶标信息
IARS is a member of aminoacyl-tRNA synthetases which catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ20736; IRS; isoleucine tRNA ligase 1, cytoplasmic; Isoleucine--tRNA ligase, cytoplasmic; Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase, cytoplasmic
基因别名: IARS; IARS1; ILERS; ILRS; IRS; PRO0785
UniProt ID: (Human) P41252
Entrez Gene ID: (Human) 3376
