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IARS Antibody (PA5-78012) in IHC (P)
IARS Polyclonal Antibody detects IARS protein at cytoplasm in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. IARS Polyclonal Antibody (Product # PA5-78012) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
PA5-78012
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human IARS. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.45 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2735944
产品详细信息
Positive Control: 293T, A431, HeLa, HepG2
Predicted Reactivity: Mouse (92%), Xenopus laevis (80%), Bovine (94%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
IARS is a member of aminoacyl-tRNA synthetases which catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ20736; IRS; isoleucine tRNA ligase 1, cytoplasmic; isoleucine tRNA synthetase; Isoleucine--tRNA ligase, cytoplasmic; isoleucine-tRNA synthetase; isoleucyl tRNA synthetase; Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase, cytoplasmic
基因别名: IARS; IARS1; Iarsl; ILERS; ILRS; IRS; PRO0785
UniProt ID: (Human) P41252
Entrez Gene ID: (Human) 3376, (Rat) 306804
