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产品信息
PA5-55015
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2642605
产品详细信息
Immunogen sequence: NVIHPDVVVN GGQDQSKEPP YGADVLRWWV ADSNVFTEVA IGPSVLNAAR DDISKLRNTL RFLLGNVADF NPETDSIPVN DMYV
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 77%.
靶标信息
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is in a hormone independent manner, but when Trip230 forms a complex with TR, it is in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting that phosphorylation may be important for its nuclear translocation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 6.1.1.5; IleRS; isoleucine tRNA ligase 2, mitochondrial; Isoleucine--tRNA ligase, mitochondrial; isoleucine-tRNA synthetase 2, mitochondrial; Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase, mitochondrial; mitochondrial isoleucine tRNA synthetase
基因别名: CAGSSS; IARS2; ILERS
UniProt ID: (Human) Q9NSE4
Entrez Gene ID: (Human) 55699
