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产品信息
PA5-103366
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human IBTK(Accession Q9P2D0), corresponding to amino acid residues V1224-T1274.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852710
产品详细信息
Antibody detects endogenous levels of total IBTK.
靶标信息
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bruton agammaglobulinemia tyrosine kinase inhibitor; BTK-binding protein; IBtk; Inhibitor of Bruton tyrosine kinase; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma; RP1-93K22.1
基因别名: BTBD26; BTKI; IBTK; KIAA1417
UniProt ID: (Human) Q9P2D0
Entrez Gene ID: (Human) 25998
