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Peptide sequence: SKAIVLYQKR ICFLSQEENE LGKFLRSQGF QDKTRAGKMM QATGKALCFS
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 69 kDa islet cell autoantigen; diabetes mellitus type I autoantigen; ICA69; ICAp69; Islet cell autoantigen 1; islet cell autoantigen 1 isoform; islet cell autoantigen 1, 69kDa; Islet cell autoantigen p69; p69; testicular tissue protein Li 162
基因别名: ICA1; ICA69; ICAp69
UniProt ID: (Human) Q05084
Entrez Gene ID: (Human) 3382