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产品信息
PA5-100267
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ICMT(Accession O60725), corresponding to amino acid residues H92-E142.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2815797
产品详细信息
Antibody detects endogenous levels of total ICMT.
靶标信息
This gene encodes the third of three enzymes that post translationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Farnesyl cysteine carboxyl methyltransferase; FCMT; Isoprenylcysteine carboxylmethyltransferase; MGC39955; pcCMT; PPMT; Prenylated protein carboxyl methyltransferase; prenylcysteine carboxyl methlytransferase; Prenylcysteine carboxyl methyltransferase; protein-S isoprenylcysteine O-methyltransferase; Protein-S-isoprenylcysteine O-methyltransferase
基因别名: 1700008E11Rik; C80758; fcmt; Gm13095; HSTE14; ICMT; MST098; MSTP098; OTTMUSG00000010406; PCCMT; PCMT; PPMT; STE14
UniProt ID: (Human) O60725, (Rat) Q9WVM4, (Mouse) Q9EQK7
Entrez Gene ID: (Human) 23463, (Rat) 170818, (Mouse) 57295
cellular protein modification process
C-terminal protein methylation
protein targeting to membrane
post-translational protein modification
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
in utero embryonic development
liver development
protein methylation
protein localization
positive regulation of cell proliferation
multicellular organism growth
regulation of Ras protein signal transduction
regulation of nucleic acid-templated transcription
regulation of RNA biosynthetic process
methylation
